T. Farghaly
Mar 1, 2008
Citations
0
Influential Citations
4
Citations
Journal
Journal of Chemical Research
Abstract
3-Acetyl-1,7-diphenyl[1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-one (1) reacts with N,N-dimethylformamide dimethylacetal (DMFDMA) yielding the enaminone 2. The latter compound reacts with active methylene compounds, hydrazine hydrate, hydroxylamine and some heterocyclic amines to afford trisubstituted pyridine, substituted pyrazole, substituted isoxazole and azolopyrimidines. The antimicrobial activities of the compounds prepared were screened.