A. Krutošíková, M. Dandárová, J. Alföldi
1993
Citations
0
Influential Citations
5
Citations
Journal
Collection of Czechoslovak Chemical Communications
Abstract
The synthesis of ethyl 2-formyl-4-benzylfuro[3,2- b ]pyrrole-5-carboxylate ( I ) is described. A series of furo[3,2- b ]pyrrole-2-carbaldehyde 2,6-dialkylphenylhydrazones ( IIa - IIg ) and dimethylhydrazones ( IIIa - IIId ) were prepared. By reaction of title compounds with hydroxylammonium chloride in acetic anhydride in the presence of pyridine corresponding cyano-substituted compounds ( IVa - IVd ) were obtained. Alkaline hydrolysis of IVa - IVd gave Va - Vb and the reaction with sodium azide and ammonium chloride in dimethylformamide led to VIa - VId . the structure of the compounds have been proved by UV, IR, 1 H and 13 C NMR spectra.