E. A. Bakhite, A. Abdel-rahman, O. Mohamed
2002
Citations
0
Influential Citations
17
Citations
Journal
Bulletin of The Korean Chemical Society
Abstract
4-Aryl-3-cyano-6-(2'-thienyl)-pyridine-2(1 H)-thiones (1a-c) were reacted with phenacyl bromide, chloro- Narylacetamides or 2-chloroacetylaminopyridine to furnish 2-functionalized 3-amino-4-aryl-6-(2'-thienyl)thieno[2,3-b]pyridines 4a-c and 5a-c or 5d respectively. The compounds 5a-d underwent different sequence of reactions to produce a variety of thienylpyridothienopyrimidines and, thienylpyridothienotriazines. Some of the prepared compounds were tested in vitro for their antimicrobial activities.