S. Florio, J. Leng, C. Stirling
Mar 1, 1982
Citations
0
Influential Citations
11
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
A series of derivatives of 4H-2,3-dihydrobenzo-1,4-thiazine has been prepared. 4-Acetyl-2,3-dihydrobenzo-1,4-thiazine undergoes self-condensation by n-butylmagnesium bromide affording the corresponding 4-aceto-acetyl-2,3-dihydrobenzo-1,4-thiazine, which, is converted to 5H-1,4-thiazino[2,3,4-if]quinolin-5-one. Halogena-tion of the acetyl derivative takes place at the position 2 of the heterocyclic ring and oxidation leads to 1-oxides and 1,1-dioxides.