L. Bobkova
Sep 15, 2015
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Journal
Chemistry and Chemical Technology
Abstract
The interaction of pyridine-4(-3,-2)aldoxime has been studied whit 3-bromo-N,N,N-trialkyl-2oxo(-hydroxyimino)-1-propanaminium bromide. The structure of all synthesized compounds was determined by elemental analysis as well as by physical and chemical methods. All synthesized compounds were tested for reactivation of phosphorylated acetylcholinesterase. Using fragments of the molecules (an oxime group, 3-bromoN,N,N-trimethyl(or triethyl)ammonium [(or N-methylmorpholinium)-2-oxo(or 2-hydroxyimino)]propan bromides), a new series of pyridinium-aldoxime salt (cholinesterase reactivator) was obtained.