M. Legraverend, H. Boumchita, E. Bisagni
1991
Citations
0
Influential Citations
17
Citations
Journal
Heterocycles
Abstract
Two ring-expanded analogues (compouds 13 and 14)of the anti-HIV agents cyclobut-A and cyclobut-G are described. They were synthesized from trans-3,4-bis-(hydroxymethyl)cyclobutylamine which was obtained from threo-3,4-bis(methoxycarbonyl)-hexane dioic acid. Neither compound (13, 14) was able to provide protection to CEM cells against HIV-1 infection