Naixing Wang, Xinliang Tang
Jul 30, 2009
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Influential Citations
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Journal
Science China-chemistry
Abstract
R-Enantiomer of the β-receptor antagonist N-[3-acetyl-4-(2-hydroxy-3-isopropylamino-propoxy)phenyl] butanamide with high enantioselectivity was synthesized from cheap starting materials and enantiopure chiral reagent through an efficient, convenient and practical synthetic strategy. Title product was detected by 1H NMR, 13C NMR, and MS, and the enatiomeric excess was determined by chiral HPLC analysis using a chiracel AD-H column.