A. Popkov, I. Císařová, J. Sopková
2005
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0
Influential Citations
11
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Journal
Collection of Czechoslovak Chemical Communications
Abstract
The recently published environmentally friendly preparation of a glycine synthon 2 from regeneratable chiral auxiliary BPB (( S )- N -(2-benzoylphenyl)- N' -benzylprolinamide) was used for preparative asymmetric synthesis of the non-coded amino acid 3-(1-naphthyl)alanine ( 1 ). Full assignment of 1 H and 13 C NMR of both intermediate complex 3 and 1 and X-ray structure determination of complex 3 were made. Cotton effects observed in circular dichroism spectrum of complex 3 are consistent with published empirical rules.