H. SanchezIgnacio, TallabsF. Ramón
Jul 5, 1981
Citations
0
Influential Citations
9
Citations
Journal
Chemistry Letters
Abstract
A new method of synthesis of Sceletium (Aizoaceae) alkaloids based on the introduction of a “formyl anion” equivalent at the β-position of a cinnamonitrile, followed by Robinson annulation and final modification of the resulting cyanomethyl side chain is described. The method has been successfully applied to the total synthesis of racemic O-methyljoubertiamine (1) and mesembrine (2).