Shide Shen, Wei-Hua Yang, Chenxia Yu
Sep 1, 2012
Citations
0
Influential Citations
2
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
A series of 2-(phenylamino)-4-(trifluoromethyl)-1,6-dihydropyrimidine derivatives were synthesized efficienly via the reaction of aryl aldehyde, ethyl 4,4,4-trifluoro-3-oxobutanoate and 1-phenylguanidine carbonate catalyzed by sulfamic acid under solvent-free conditions. This protocol has the advantages of mild condition, high yields and environmentally benign procedure.