Zhang Sheng-ju
2008
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Journal
Chemical Reagents
Abstract
A new compound 7-(3-amino-3-arylpropanoyl)-3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo [4,3-α]piperazine was synthesized from 2-chloropyrazine and 3-amino-3-arylpropionic acids through a series of reactions including hydrazinolysis,trifluoroacetylation,cyclization,hydrogenation,condensation and deprotection.The structure of the title compound was characterized by IR,1HNMR,13CNMR and MS.