J. Corrie
Apr 1, 1996
Citations
0
Influential Citations
2
Citations
Journal
Journal of Labelled Compounds and Radiopharmaceuticals
Abstract
Nitration of 1-phenylethyl acetate with NH 4 NO 3 -trifluoroacetic anhydride gave a mixture of ortho- and para-nitro products, which were separable by chromatography after saponification of the acetate. The ortho-isomer [1-(2-nitrophenyl)ethanol] was converted to the 1-(2-nitrophenyl)ethyl esters of monomethyl phosphate and of the γ-phosphate of ATP. The title isotopomers were prepared using either ammonium [ 15 N]nitrate or [side-chain 1- 13 C]1-phenylethyl acetate as starting materials. A correction is made to the reported 1 H NMR spectrum of caged ATP and the effects of isotopic substitution on the mass spectral fragmentation of 1-(2-nitrophenyl)ethanol are tabulated