J. Pandey, R. Pal, A. Dwivedi
Jan 1, 2002
Citations
0
Influential Citations
24
Citations
Quality indicators
Journal
Arzneimittelforschung
Abstract
Summary l,2-Bis(4-substituted phenyl)-2-methyl ethanone (2,4-dlnitrophenyl)hydrazones and 1-naphthyl-1-(4-substituted phenyl)-methanone (2,4-dinitrophenyl)hydrazones have been synthesized and evaluated for their anti-implantation, uterotrophic, antiuterotrophic, anticancer and antimicrobial activities. Diphenolic hy-drazone (compound 6) showed maximum uterotrophic inhibition of 70 %, whereas compound 20 exhibited cytotoxicity in the range of 50–70 % against MCF-7 and ZR-75-1 human malignant breast cell lines.