M. Sayed, A. El-Dean, Mostafa Ahmed
May 25, 2017
Citations
0
Influential Citations
7
Citations
Journal
European Chemical Bulletin
Abstract
3-chloro-1H-Indole-2-Carbaldehyde ( 4 ) was synthesized and converted into Schiff base derivatives ( 5a-c ). Compounds ( 5a-b ) were reacted with chloro acetyl chloride to give 2-Azetidinone derivatives (6a-c) . Compound (4) react with active methylene group compounds, hydrazine and phenylhydrazine derivatives underwent condensation reaction to give compounds in ( scheme 2) . compound (4) was reacted with ethyl chloro acetate derivatives to give N-alkylated Indole schiff bases (18) which underwent cyclization reaction using reagent in scheme (3) to afford Azetidinone derivatives (19) ( scheme 3 ).