Wang Wei
2009
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Journal
Chinese Journal of Spectroscopy Laboratory
Abstract
One of novel α-{[(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1-(2H)-yl)acetyl] amino}-2-methyl butyric acid was synthesized by carbodiimide of peptide coupling reaction with 5-fluorouracil-1-yl acetic acid,N,N'-dicyclohexylcarbo-diimide (DCC),L-valine acid as a raw material,1-Hydroxybenzotrizole(BtOH) as auxiliary reagents,and characterized by IR spectra and elemental analyses of evidence "5-Fluorouracil short peptide" structure.