B. Amos-Tautua, O. Fakayode, S. Songca
Sep 16, 2020
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0
Influential Citations
5
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Journal
ChemRN: Medicinal Chemistry (Topic)
Abstract
Singlet oxygen is a valuable reactive oxygen species known for its effective action on the elimination of cancers and age-related eye disease such as macular degeneration. In this study, 5,10,15,20-tetrakis (3,5-dimethoxyphenyl) porphyrin was synthesized and characterized using various spectroscopic methods. The λmax for the Soret and Q bands were 417 nm and 514, 547, 589 and 646 (nm) respectively. The estimated singlet oxygen yield (φΔ) for the porphyrin was higher than some literature reports, suggesting a stronger potential of the porphyrin for the photosensitizing photodynamic treatment of cancer and other related human disorders.