B. Das, M. Krishnaiah, C. Sudhakar
Apr 1, 2010
Citations
0
Influential Citations
9
Citations
Journal
Bioorganic & medicinal chemistry letters
Abstract
The stereoselective synthesis of two naturally occurring bioactive spiroacetals, aculeatins A and B has been accomplished using 1-tetradecanal as the starting material. The sequence introduces diastereoselective iodine-induced electrophilic cyclization and ring opening of epoxide with 1,3-dithiane as the key steps.