Farina Brackmann, M. Es-Sayed*, A. Meijere
Jun 1, 2005
Citations
0
Influential Citations
5
Citations
Journal
European Journal of Organic Chemistry
Abstract
Methyl 1-(tert-butoxycarbonylamino)cyclopropanecarboxylate (9) was converted into the spirocyclopropanated five-membered ring analogue 7a of Iprodione (1) in five steps with an overall yield of 28 %. The spirocyclopropanated five-membered ring analogue 8a was prepared from tert-butyl N-[1-(hydroxymethyl)cyclopropyl]carbamate (10) in five steps with an overall yield of 19 %. En route to the spirocyclopropanated six-membered ring analogues of Iprodione (1), the oxalic acid diamides 5b and 6b could be obtained starting from 9 or 10 in 33 or 19 % yield, respectively. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005)