S. Tanimori, Kouji Fukubayashi, M. Kirihata
Jan 1, 2000
Citations
0
Influential Citations
7
Citations
Journal
Bioscience, Biotechnology, and Biochemistry
Abstract
2,6,6-Trimethyl-2-azaspiro[4.4]nonane-1,3-dione (9), a spirosuccinimide moiety of asperparaline A (1), was synthesized by starting from 2,2-dimethylcyclopentanone (4) via trinitrile 6 in five steps in a moderate yield. This conversion establishes a model study for synthesis of the spirosuccinimide moiety of asperparaline A (1).