B. Reddy, V. Swathi, M. Swain
Dec 8, 2014
Citations
0
Influential Citations
41
Citations
Journal
Organic letters
Abstract
A variety of aldehydes undergo smooth coupling with 4-hydroxy-N-methyl-2-methylene-N-phenylbutanamide in the presence of BF3·OEt2 under ambient conditions to produce the corresponding spiro-oxindole derivatives in good yields with excellent selectivity. It is an entirely new strategy to construct the spirocycles in a one-pot operation through a Prins cascade process.