Khadijah Hindi, T. Siciliano, S. Durmus
Feb 21, 2008
Citations
1
Influential Citations
176
Citations
Quality indicators
Journal
Journal of medicinal chemistry
Abstract
A series of methylated imidazolium salts with varying substituents on the 4 and 5 positions of the imidazole ring were synthesized. These salts were reacted with silver acetate to afford their corresponding silver N-heterocyclic carbene (NHC) complexes. These complexes were then evaluated for their stability in water as well as for their antimicrobial efficacy against a variety of bacterial strains associated with cystic fibrosis and chronic lung infections.