Chen-Yi Li, Yu-Ling Lien, A. Datta
Jun 1, 2012
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Influential Citations
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Quality indicators
Journal
Journal of The Chinese Chemical Society
Abstract
A series of Cu(II) compounds containing neutral multi-dentate ligand [2,6-diisopropylphenyl]-bis[(1-H-pyrazol-1-yl)methyl]amine (L1) and pyrazole dimethoxethyl ligand [(1-H-pyrazol-1-yl)methyl]-bis(2-methoxyethyl)amine (L2) were synthesized. Reactions of L1 and L2 with copper(II) chloride generate L1CuCl2 (1) and L2CuCl2 (2), respectively. Compounds 1 and 2 have been characterized by elemental analysis and X-ray single crystal diffractometry. The effects of compounds 1 and 2 on the cell viability of various human cancer cells (including A549, COLO 205, HT-29, Hep3B, HepG2, Huh7, and PCL5 cells) were investigated. The results indicate that compound 2 has a strong inhibitory effect on cell growth in human colorectal carcinoma cells (COLO 205 cells and HT-29 cells).