W. Chui, A. Dolzhenko, N. Kolotova
2004
Citations
0
Influential Citations
6
Citations
Journal
Heterocycles
Abstract
(2-Oxo-2,3-dihydroimidazo[1,2-a]pyridin-3-yl)acetic acids (4a-c, 9a-c) were prepared from 2-aminopyridines by acylation with maleic or citraconic anhydrides and followed by Michael addition. Formation of 3-methyl substituted derivatives (9a-c) from citraconic anhydride was found to be regioselective. The molecular conformations of the products in the solution and in the crystal form were discussed based on 1 H NMR spectral and X-Ray data.