Yushun Li, D. E. Carter, E. Mash
Jan 1, 2002
Citations
0
Influential Citations
4
Citations
Journal
Synthetic Communications
Abstract
ABSTRACT A synthesis and the structure of the title compound are presented. The sodium salt of N-BOC glutathione dimethyl ester was S-alkylated with chloroacetaldehyde. Following a protection/deprotection sequence, condensation of the aldehyde moiety with the nitrogen of the cysteine residue and subsequent dehydration produced a glutathione derivative that contains a 2,3-dihydro-4H-1,4-thiazine ring.