H. Tajmir-Riahi, M. Bertrand, T. Theophanides
May 1, 1986
Citations
0
Influential Citations
23
Citations
Journal
Canadian Journal of Chemistry
Abstract
Several complexes of adenosine-5-triphosphate disodium salt (Na2H2ATP) with the metal ions, Na+, Mg2+, Ca2+, Mn2+, Co2+, Ni2+, Cu2+, and cis- and trans-Pt(NH3)2Cl2 and K2PtCl4 at pH = 3.5 and 7.2 have been isolated, identified, and studied. Marked spectral similarities have been observed for the structurally known metal–phosphate bonded compounds, [Cu(H2ATP)(phen)]2•7H2O and [Zn(H2ATP)(bipy)]2•4H2O and all the metal–ATP complexes studied here, except the Pt–ATP complexes. The metal binding is through the α, β, and γ phosphate oxygen atoms when the N1-position of adenine is protonated. Spectral changes have also been observed for the Pt–ATP complexes in which there is a Pt–N7 and –N1 coordination. The sugar pucker in the Na2H2ATP•3H2O crystal dimers is C3′-endo–anti (in one) and C2′-endo–anti (in the other) with a characteristic infrared band at 818 cm−1. In the corresponding Cu2+ and Zn2+ complexes the sugar has C3′-endo–anti conformation with the marker band at about 814 cm−1. The C2′-endo–anti conformat...