I. Ukrainets, O. Gorokhova, K. V. Andreeva
Feb 14, 2014
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Journal
Russian Journal of Organic Chemistry
Abstract
Treatment of 1-(2-cyanoethyl)-4-hydroxy-N-(hydroxyalkyl)-2-oxo-1,2-dihydroquinoline-3-carboxamides with a solution of hydrogen chloride in aqueous acetic acid ensures selective transformation of the cyano group into amide or carboxy with simultaneous acetylation of the hydroxyalkyl fragments.