H. Sai, Y. Ozaki, K. Hayashi
Jun 15, 1996
Citations
0
Influential Citations
4
Citations
Journal
Chemical & pharmaceutical bulletin
Abstract
Trimebutine derivatives were synthesized by utilizing alkylation or acylation of isonitriles and nitrile as a key step. The colonic contractile effects of these compounds were examined, and T-1815 was found to have strong colonic propulsive activity.