Wei Su, Zhaofeng Tang, Qi Xiao
May 1, 2015
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0
Influential Citations
22
Citations
Journal
Journal of Organometallic Chemistry
Abstract
Abstract A series of [( p -cymene)Ru(TSC)Cl]Cl compounds ([ 1 ]Cl, [ 2 ]Cl and [ 3 ]Cl) and their corresponding [( p -cymene)Ru(TSC)Cl][( p -cymene)RuCl 3 ] derivatives ([ 1 ][( p -cymene)RuCl 3 ], [ 2 ][( p -cymene)RuCl 3 ] and [ 3 ][( p -cymene)RuCl 3 ]) have been synthesized and characterized by H 1 NMR, elemental analysis and HR-ESI-mass spectrometry. The molecular structures of [ 2 ]Cl, [ 3 ]Cl, [ 1 ][( p -cymene)RuCl 3 ], [ 2 ][( p -cymene)RuCl 3 ] and [ 3 ][( p -cymene)RuCl 3 ] have been characterized by single-crystal X-ray diffraction analysis. The complexes have been further evaluated for their in vitro antiproliferative activities against the SGC-7901 human gastric cancer, BEL-7404 human liver cancer and HEK-293T noncancerous cell lines. Furthermore, the interactions of the complexes [ 1 ]Cl and [ 1 ][( p -cymene)RuCl 3 ] with HSA have been followed by fluorescence spectrometry studies.