Janardhana Nayak, P. Dayananda, V. D'Souza
Dec 1, 2019
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Chemical Data Collections
Abstract
Abstract Twelve novel (E)-N-((2-chloro-6-substituted quinolin-3-yl)methylene)-4-(substituted phenyl)-6-phenyl-2H-1,3-thiazin-2-amines were synthesized by the reaction of 6-substituted- 2-chloro quinoline-3-carbaldehydes with 4-substituted phenyl-6-phenyl-6H-1,3-thiazin-2-amines. The structures of some of the compounds were characterized by FT-IR, NMR and Mass Spectral analysis. Synthetic compounds were also screened for their antifungal and antibacterial activity. Most of them showed significant activity comparable with that of the standard.