N. Zanatta, C. C. Madruga, Patricia C. Marisco
2008
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Influential Citations
8
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Journal
Journal of Heterocyclic Chemistry
Abstract
This work describes the synthesis of a novel series of 2-methylsulfanyl-tetrahydropyrimidines, from the cyclocondensation reaction of β-alkoxyvinyl trihalomethyl ketones with 2-methyl-2-thiopseudourea sulfate, in good yields. A detailed 1H- and 13C-NMR study was performed on the 2-methylsulfanyl-tetrahydropyrimidines obtained and 3D structures were proposed based on AM1 calculations supported by 1H NMR coupling constants and NOESY experiments.