Chieh‐Kai Chan, Yu-Hsin Chen, Yu-Lin Tsai
Mar 7, 2017
Citations
0
Influential Citations
18
Citations
Journal
The Journal of organic chemistry
Abstract
In this work, we developed a concise synthetic route for the synthesis of polysubstituted naphthalenes starting from commercially available isovanillin and its derivatives. Reaction with styryl bromide via O-styrylation, Claisen rearrangement, ene reaction, and O-alkylation occurred in high yields. The key structures were confirmed by single-crystal X-ray diffraction.