Gang Shan, Xiuyun Sun, Q. Xia
Oct 3, 2011
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Influential Citations
36
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Journal
Organic letters
Abstract
An efficient single-step approach toward the synthesis of 2-alkylquinolines is described. Through a Lewis acid mediated [3+3] annulation reaction between 3-ethoxycyclobutanones and aromatic amines, a variety of multisubstituted 2-alkylquinoline derivatives were prepared regioselectively at room temperature.