W. Speckamp, J. Dijkink, A.W.J.D. Dekkers
1971
Citations
0
Influential Citations
25
Citations
Journal
Tetrahedron
Abstract
Abstract The synthesis of 3-azabicyclo[3.3.1]nonanes is described via the addition of α-bromomethylacrylate 1 to N-tosylpiperidone enamine 4 and subsequent transformation of these adducts. A brief discussion is given on some mechanistic aspects of the addition. NMR-investigation of the various compounds showed a fair correlation between structure and conformation of the adducts and the observed chemical shifts of C H -COOR and N-C H 2 protons.