P. Weller, R. Hanzlik
Sep 1, 1988
Citations
0
Influential Citations
5
Citations
Journal
Journal of Labelled Compounds and Radiopharmaceuticals
Abstract
The synthesis of [14C]-labeled bromobenzene, 2-bromophenol, 4-bromophenol, 1,2-dibromobenzene, 2-bromobenzonitrile, 2-bromotoluene, and 2-bromoanisole are reported. [14C]-Aniline is selectively monobrominated to ortho-and para-bromoanilines in 5 to 3 ratio. The separated bromoanilines are diazotized and either reduced, hydrolyzed, coupled to bromide, coupled to cyanide, or coupled to carbon. 2-Bromophenol is O-methylated to 2-bromoanisole.