Ju Liu, Xuechen Hao, Ye Chen
Jan 1, 2017
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0
Influential Citations
2
Citations
Journal
Journal of Chemical Research
Abstract
A series of novel substituted 5-amino-8H-phthalazino[1,2-b]quinazolin-8-one derivatives synthesised by condensation of different amines with 5-chloro-8H-phthalazino[1,2-b]quinazolin-8-one, which was prepared from methyl 2-aminobenzoate by condensation with hydrazine hydrate and then cyclisation with a phthalic anhydride in N,N-dimethylacetamide at refluxing condition. The intermediate and target compounds were obtained in good yields and were easily purified by filtration or recrystallisation.