E. I. Sorochinskaya, L. I. Leont’eva, V. F. Martynov
Mar 1, 1988
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Journal
Chemistry of Natural Compounds
Abstract
Four different schemes for the synthesis by the classical method of pyroglutamylasparaginylglycine — a suggested aggression peptide have been described. The best is a scheme using C- and N-terminal protective groups of the benzyl type at the stage of obtaining the protected tripeptide. Literature information according to which the compound possesses biological activity has been refuted.