X. Zhong, Jianwei Guo, S. Fu
Mar 25, 2014
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0
Influential Citations
16
Citations
Journal
Journal of Surfactants and Detergents
Abstract
A series of novel cationic gemini surfactants, namely 1,3-adamantanedicarboxylic acid bis(alkyldimethyl-3-ammoniopropyl amide) dibromide designated as [Ad-2(amCn)] (n = 12, 14, 16), containing adamantane, two amide groups, and two hydrocarbon chains, were synthesized from 1,3-adamantanedicarboxylic acid. The surface-active properties of the surfactants were investigated through surface tension and electrical conductivity measurement. A series of thermodynamic parameters such as standard free energy $$\left( {\Delta G^\circ_{\text{m}} } \right)$$ΔGm∘, enthalpy $$\left( {\Delta H^\circ_{\text{m}} } \right)$$ΔHm∘, and entropy $$\left( {\Delta S^\circ_{\text{m}} } \right)$$ΔSm∘ of micellization were evaluated from electrical conductivity measurements in the temperature range from 288 to 308 K. The micellization for [Ad-2(amCn)] is entropy-driven at low temperature and enthalpy-driven at high temperature. Further, the antimicrobial activity of the synthesized gemini surfactants against both Gram-positive and Gram-negative bacteria was also investigated, and this study showed that the compound [Ad-2(amC12)] has excellent antibacterial activity against all studied bacteria.