Vassilios N. Kourafalos, P. Marakos, E. Mikros
Dec 18, 2006
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Influential Citations
11
Citations
Journal
Tetrahedron
Abstract
Abstract A number of 7-substituted pyrazolo[3,4-c]pyridine derivatives have been synthesized in order to investigate the N1–N2 tautomerism within this class of biologically interesting compounds. Tautomeric equilibrium has been studied using NMR 13C, 15N chemical shifts and heteronuclear 1H–15N and 1H–13C spin–spin couplings, in conjunction with X-ray crystallography. The N1 tautomer predominates in DMF solution in all the compounds tested.