Xue Hua-ping
2007
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Journal
Qilu Pharmaceutical Affairs
Abstract
OBJECTIVE To improve the synthetic procedure of terazosin hydrochloride.METHODS Terazosin hydrochloride was synthesized from anhydro-piperazine via acylation,reduction,amination,salification etc.RESULTS and CONCLUSION The new method can reduce the cost,enhance the yield,and it was suitabale for pharmaceutical industry.