J. Wolfe, M. A. Rossi
Jan 23, 2004
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1
Influential Citations
115
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Journal
Journal of the American Chemical Society
Abstract
A new, stereoselective method for the synthesis of substituted tetrahydrofurans from gamma-hydroxy alkenes that forms both a C-C and a C-O bond with diastereoselectivities of up to >20:1 is described. Initial mechanistic studies that suggest the reactions proceed via the intramolecular insertion of an olefin into a Pd(Ar)(OR) intermediate are discussed.