A. Ran
2012
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Journal
Fine Chemical Intermediates
Abstract
The titled compound was synthesized,via steps of reduction,halogenation,reaction with 7-aminoheptanoic acid ethyl ester hydrochloride and alkaline hydrolysis,using dibenzothiazepin-11(6H)-one-2-chloro-6-methyl-5,5-dioxide as the starting material.The process has the advantages of low costs,mild reaction conditions,simple operation and suitable for industrial production.