I. L. Aleqsanyan, L. Hambardzumyan
Aug 1, 2021
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Journal
Russian Journal of Organic Chemistry
Abstract
Novel hetarylquinolines containing the thiazolidine and dihydrothiazole rings were synthesized on the basis of benzene ring–substituted 2-{4-[2-methyl-4-(methylsulfanyl)quinolin-3-yl]butan-2-ylidene}hydrazinocarbothioamides. The reactions of the latter and their sulfanyl analogs with phenylhydrazine hydrochloride gave benzene ring–substituted 2-methyl-3-[(2-methyl-1H-indol-3-yl)methyl]-4-(methylsulfanyl)quinolines and 4-[2-methyl-4-(ethylsulfanyl)quinolin-3-yl]butan-2-ones, respectively. The latter were also prepared by the reactions of 4-(4-sulfanyl-2-methylquinolin-3-yl)butan-2-ones with ethanol in the presence of sulfuric acid.