Vaijayanti A. Kumar, Meena
May 1, 2003
Citations
0
Influential Citations
5
Citations
Journal
Nucleosides, Nucleotides & Nucleic Acids
Abstract
Abstract To delineate the binding preferences of stereochemically divergent pyrrolidine PNAs, synthesis of all four diastreomeric monomers of I and the systematic complexation studies of the resultant PNAs with complementary DNA/RNA is essential. We herein report the synthesis of trans-L/D-2-(tert-butoxycarbonylaminomethyl)-4-(thymin-1-yl) pyrrolidin-1-yl acetic acids I, their incorporation in PNA oligomers and DNA binding studies will be presented.