A. V. Velikorodov
Feb 1, 2004
Citations
0
Influential Citations
3
Citations
Journal
Russian Journal of Organic Chemistry
Abstract
By alkylation of methyl-N-(4-hydroxyphenyl)carbamate with (chloromethyl)oxirane in acetone in the presence of K2CO3 methyl-N-[4-(2,3-epoxypropoxy)phenyl]carbamate was prepared. The aminolysis of the latter effected by benzylamine, morpholine, piperidine, and pyrrolidine occurs in keeping with Krasusky rule to afford methyl-N-[4-(3-R-amino-2-hydroxypropoxy)phenyl]carbamates.