Wu Wen-liang
2011
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Zhejiang Chemical Industry
Abstract
Venlafaxine hydrochloride was synthesized from 4-methoxyphenylacetonitrile by four steps,with Assay(HPLC) of 99.5% and total yield of 77.1%.This method is a suitable industrial synthetic route with advant-ages of convenient operation,cheap materials,high yield of reductive reaction,and less pollution to environ-ment.