L. Zuo
2014
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Journal
Fine Chemical Intermediates
Abstract
5-Benzyloxy-2-(4-benzyloxyphenyl)-3-methyl-1H-indole was synthesized from 4-nitrophenol and 1-(4-hydroxyphenyl)propan-1-one by reactions of benzylation, reduction, bromination and the Bischler-M 觟hlau synthesis. This synthetic procedure is suitable for industrial preparation which has advantages of low cost, mild conditions, less side reactions and high yield.