Edward T. Castellana, D. Russell
Sep 21, 2007
Citations
2
Influential Citations
75
Citations
Quality indicators
Journal
Nano letters
Abstract
Gold nanoparticles capped with 4-aminothiophenol have been employed for laser desorption ionization mass spectrometry of biomolecules. We demonstrate that the capped nanoparticles increase ion yields, decrease ion fragmentation, and increase the useful analyte mass range when compared to other nanoparticle systems. These results will allow for further development of nanoparticles with both targeting and enhanced ionization abilities to aid in biomarker screening.