Satyasheel Sharma, E. Park, Jihye Park
Jan 20, 2012
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Organic letters
Abstract
The rhodium-catalyzed oxidative acylation between secondary benzamides and aryl aldehydes via sp(2) C-H bond activation followed by an intramolecular cyclization is described. This method results in the direct and efficient synthesis of 3-hydroxyisoindolin-1-one building blocks.