S. Bhat, A. Vaino, W. Szarek
Dec 1, 2000
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Journal
Israel Journal of Chemistry
Abstract
As part of continuing studies on drug delivery to the human liver, a phosphonoacetate—trilactoside conjugate (12) has been synthesized in an overall yield of 23%. The shortness of the synthesis of this conjugate hinges upon a successful Michaelis—Arbuzov reaction of bromoacetamide 8 with tris-(trimethylsilyl) phosphite.