Ya‐Ching Shen, Shih-Sheng Wang, C. Chien
Jan 26, 2008
Citations
0
Influential Citations
9
Citations
Quality indicators
Journal
Journal of natural products
Abstract
Phytochemical investigation of the leaves and twigs of Taxus sumatrana afforded six new taxane diterpene esters, tasumatrols U-Z ( 1- 6). Compounds 2 and 5 contained a rare five-membered lactone ring at C-8, C-9, C-10, and C-19. The structures were established on the basis of detailed spectroscopic analyses, particularly HRESIMS and 2D NMR techniques. Compound 5 showed cytotoxicity against a human hepatoma (Hep2) cell line.